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(CHICAGO) — An early-morning apartment fire in Chicago killed four children and hospitalized two adults.

The blaze was reported around 3:30 a.m. Monday at an apartment building, located on the 11200 block of South Vernon Avenue, according to the Chicago Fire Department.

Fire officials said the fire appears to have started on the second floor, with flames trapping a number of people inside.

Four children did not make it out of the burning building alive, according to ABC’s Chicago station WLS-TV, while two adults had to jump to escape.

“As I was coming out the front door, two people came flying out the window,” one tenant, Albert Miller, told WLS-TV. “A lady and a man hit the ground.”

The man and the woman were taken to an area hospital in critical condition.

The cause of the blaze remains under investigation.

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